Influenza Virus H5n1

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The viruses bind to a cell through interactions between its hemagglutinin glycoprotein and sialic acid sugars on the surfaces of epithelial cells in the lung and throat (Stage 1 in infection figure). The cell imports the virus by endocytosis. In the acidic endosome, part of the hemagglutinin protein fuses the viral envelope with the vacuole's membrane, releasing the viral RNA (vRNA) molecules, accessory proteins and RNA-dependent RNA polymerase into the cytoplasm (Stage 2). These proteins and vRNA form a complex that is transported into the cell nucleus, where the RNA-dependent RNA polymerase begins transcribing complementary positive-sense cRNA (Steps 3a and b). The cRNA is either exported into the cytoplasm and translated (step 4), or remains in the nucleus. Newly synthesised viral proteins are either secreted through the Golgi apparatus onto the cell surface (in the case of neuraminidase and hemagglutinin, step 5b) or transported back into the nucleus to bind vRNA and form new viral genome particles (step 5a). Other viral proteins have multiple actions in the host cell, including degrading cellular mRNA and using the released nucleotides for vRNA synthesis and also inhibiting translation of host-cell mRNAs.

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H5N1 Biosecurity Threat | reBlog
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Colored particle of Flu virus H1N1 H5N1 influenza A virus ...
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H5N1 controversial paper shows that bird flu is only a ...
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H5N1 Influenza Virus – Airbourne Strain Made by Virologists!
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Influenza H5N1 virus versus ferrets, round two
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VDU's blog: H5N1: 1st fatal case in North America ...
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H5N1 Virus ☆ Virology Course ☆ Lecture #25 - YouTube
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Should we fear avian H5N1 influenza?
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Sloppy practices by CDC scientist cited in lab mishap
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H5N1 Virus R2 - YouTube
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Animated Avian Flu Virus, H5N1 Stock Animation | 3388449
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Colored particle of Flu virus H1N1 H5N1 influenza A virus ...
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Animated Avian Flu Virus, H5N1. Stock Footage - YouTube
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The changing nature of avian influenza A virus (H5N1 ...
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Avian Influenza A H5N1 Virus - Quip Labs
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Influenza Virus Neuraminidase (H5N1) - The Native Antigen ...
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After epic debate, avian flu research sees light of day
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Influenza Virus Hemagglutinin (HA) (H5N1) - The Native ...
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Vogelgrippe H5N1 – Wikipedia
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INFLUENZA VIRUS
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Sharing H5N1 Viruses to Stop a Global Influenza Pandemic
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H5N1: Bird flu questions and answers - Health - CBC News
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Virus influenza A H5N1
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Baxter H5N1 Vaccine Claims
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Avian Influenza A Virus Infections in Humans | Avian ...
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H5N1 Avian flu symptoms — Stock Vector © elenabs #102248116

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